18º Congresso Brasileiro de Neurologia Infantil

Dados do Trabalho


Título

EPILEPSY AND TREATMENT CHALLENGES IN CHILDREN

Introdução

Epilepsy is characterized as a brain dysfunction with a predisposition to cause epileptic seizures. Most cases arise in childhood, and it is a challenge to achieve the best treatment for each child.

Objetivo

To analyze the proposed treatments for epilepsy in children in order to indicate the most likely to increase their quality of life.

Método

This is a review of literature and articles from the Scielo and PubMed platforms, with descriptors “Epilepsy”; “Child”; “Treatment” connected by “and”. They were selected by reading, with inclusion and exclusion criteria, excluding the repeated and unavailable ones, including works from the last 7 years, totaling 6 references.

Resultados e Conclusões

Results: Treatments vary depending on the type of epilepsy of each child and the time of diagnosis. Treatment with antiepileptic drugs reduces recurrence in the first two years after the first seizure, however, the impasse is that in the long term it does not reduce the risk of epilepsy. In addition, the ketogenic diet proved to be beneficial for the prevention of epileptic events, as it reduces neuronal excitability, which improves the control of cirrhosis. In addition, surgical treatment can reduce the recurrence of seizures, with a better prognosis in children diagnosed less than 2 years ago. Conclusion: Thus, the treatment of epilepsy in children is still full of challenges, since it must be based on a holistic approach, also considering its associated comorbidities. The ideal is to include a multidisciplinary team to control crises and ensure a better quality of life.

Palavras Chave

Epilepsy, child, treatment.

Declaração de conflito de interesses de TODOS os autores

Todos os autores declaram não ter conflito de interesse.

Fonte de Fomento (se houver)

Referências (se houver)

ABERASTURY, M. et al.. Cirugía de la epilepsia en niños y adolescentes: experiencia de 43 casos Arch. argent. pediatr. vol.114 no.5 Buenos Aires oct. 2016.

Holmes GL. Drug Treatment of Epilepsy Neuropsychiatric Comorbidities in Children. Paediatr Drugs. 2021 Jan;23(1):55-73. doi: 10.1007/s40272-020-00428-w.

MACHADO, I. V.; PÉREZ, L. E.; ABREU, D. G. Dieta cetogénica en el tratamiento de la epilepsia refractaria en niños. Humanidades Médicas 2015;15(2):373-381

MAIA, C. et al.. Risk of recurrence after a first unprovoked seizure in children. Jornal de Pediatria, v. 93, n. 3, p. 281–286, maio 2017.

PRUDENCIO, M. B. et al.. Ketogenic food pyramid for patients with refractory epilepsy: From theory to clinical practice. Revista de Nutrição, v. 30, n. 1, p. 99–108, jan. 2017.

ZUBERI, S. M.; SYMONDS, J. D. Update on diagnosis and management of childhood epilepsies. J Pediatr (Rio J). 2015;91:S67---77.

Área

Epilepsias

Autores

CLARA AZEVEDO, AMANDHA ESPAVIER TRÉS, WILLA DANIELA SOUZA PEREIRA MEIRELES