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Título

A NEW CHAPTER IN CLINICAL PRACTICE: MAIN NEUROLOGICAL MANIFESTATIONS OF COVID-19-ASSOCIATED MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN

Introdução

Pediatric Multisystem Inflammatory Syndrome (P-SIM) associated with COVID-19 is characterized by a post-viral multiorgan hyperinflammatory condition with a higher incidence between two and four weeks after infection with the SARS-Cov-2 virus. This newly identified and rare health condition leads to a serious condition with involvement and complications of various organs and systems. In this sense, the neurological involvement caused by SIM-P is one of the prognostic factors of possible worsening of this disease.

Objetivo

This study aims to identify and analyze the main neurological manifestations of the Pediatric Multisystemic Inflammatory Syndrome associated with COVID-19 in contemporary children.

Método

This is a qualitative and descriptive research, carried out through an integrative review of the literature relevant to the objectives. For the elaboration of the article, a bibliographic survey was carried out in which 12 scientific articles and journals were tracked, consulted and selected, delimited between 2020 and 2023. This screening was carried out in the databases: Google Scholar, Scientific Electronic Library Online (Scielo), PubMed and health agency documents.

Resultados e Conclusões

Despite the negligible scientific evidence available for understanding the neurological complications of SIM-P related to the SARS-Cov-2 virus infection, it is noted that the studies consulted to compose this article report the following as the main neurological complications related to this syndrome: headache, encephalitis severe stroke, encephalopathy, dizziness, CNS infection/demyelination, acute fulminant cerebral oedema, Guillain-Barré Syndrome and epileptic seizures. With emphasis on headache, acute encephalopathy and severe encephalitis and stroke.


It appears, therefore, that it is essential to continue to carry out more research and scientific studies focused on this theme so that in the near future the scientific gaps inherent in SIM-P linked to COVID-19 are filled, since it has A new chapter has been observed in clinical practice where cases of pediatric patients with Multisystemic Inflammatory Syndrome associated with COVID-19 with neurological manifestations have been experienced. Therefore, it is essential to establish new research so that diagnosis and treatment are increasingly early, with the aim of understanding, preventing and delaying these neurological complications in the pediatric public.

Palavras Chave

Pediatric Multisystem Inflammatory Syndrome. Children. Neurological manifestations. COVID-19

Declaração de conflito de interesses de TODOS os autores

Não há conflitos de interesse por parte dos autores.

Fonte de Fomento (se houver)

Referências (se houver)

Área

Manifestações neurológicas das doenças sistêmicas