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Título

PREVALENCE OF SLEEP DISORDERS IN CHILDREN WITH CONGENITAL ZIKA VIRUS SYNDROME IN A REFERENCE SERVICE IN THE STATE OF CEARA

Introdução

In the general pediatric population, sleep disorders affect approximately 25% of children. As for neurodevelopmental disorders, 50% to 95% of individuals may have sleep disorders that constitute a risk of mitigating problematic daytime behaviors and poor cognitive and academic performance. However, the information is still available regarding whether a specific sleep profile is observed in distinct syndromes and whether these sleep problems are persistent and chronic. The development of sleep and wakefulness states begins in fetal life and is closely linked to the maturation of the Central Nervous System (CNS). Sleep problems impair child development and negatively impact learning and quality of life, being reported in children with neurological impairments. Considering the brain anomalies present in children with congenital Zika syndrome and the neurological vulnerability for sleep-wake regulation, it is likely that these children are more likely to have sleep problems.

Objetivo

Discuss the prevalence of sleep disorders evidenced in patients diagnosed with congenital Zika Virus syndrome followed in a reference service for the condition in a tertiary public hospital in the state of Ceará

Método

This was a quantitative, descriptive, retrospective, and observational study conducted from 2016 to 2018 using medical records data from a tertiary public hospital in the state of Ceará. Inclusion criteria were as follows: (1) diagnosis of CZVS and (2) availability of cranial CT or MRI images. Approval was obtained from the local ethics committee with CAAE 57109816700005042

Resultados e Conclusões

Results: In 207 cases, only 44 patients were evaluated about sleep disorders. Of the total of 44 patients, 17 (38.63%) had sleep disorders (unspecified) and 27 (61.37%) had no sleep disorders. Regarding those who had sleep disorders, 8 are female (17.7%) and 9 (20%) are male, the age of these patients ranged from 1 year and 6 months to 3 years and 3 months, at median age was 37 months.
Conclusion: Some studies cite a greater probability of children with Congenital Zika Virus Syndrome to develop sleep disorders, but the literature still cannot establish whether in fact sleep disorders are really connected to the syndrome, as there is a lack of research that investigates the relationship between changes in sleep quality in children with microcephaly and Zika virus infection. Therefore, it is necessary that more studies on the subject be carried out.

Palavras Chave

Zika Virus, microcephaly, sleep disorders

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